L.P. (Leonard) Schuele

Leonard is a junior postdoc at the Department of Viroscience. Here he applies high throughput sequencing approaches for:

i) genomic mpox virus surveillance throughout the Netherlands,

ii) viral exploration in the human-animal-environment interface, and

iii) antibody capture based metagenomic sequencing to reveal (novel) immunogenic viruses.

Application of Illumina and Nanopore sequencing in human, animal and environmental samples. Metagenomic and whole-genome sequencing with a focus on viral and bacterial pathogens.

University hospital Tuebingen: Research assistant

University Medical Center Groningen: PhD, Application of Next-Generation Sequencing in Microbiology: From Clinical Diagnostics to One Health Surveillance

Erasmus MC: Junior postdoc, Department of Viroscience

Link to Leonard’s list of publications:
https://scholar.google.de/citations?user=o8h99cMAAAAJ&hl=en&oi=ao

Circulation, viral diversity and genomic rearrangement in mpox virus in the Netherlands during the 2022 outbreak and beyond (https://doi.org/10.1002/jmv.29397)

Off-season circulation and characterization of enterovirus D68 with respiratory and neurological presentation using whole-genome sequencing (https://doi.org/10.3389/fmicb.2022.1088770)

Exploring a prolonged enterovirus C104 infection in a severely ill patient using nanopore sequencing (https://doi.org/10.1093/ve/veab109)

Evaluation of whole-genome sequence data analysis approaches for short- and long-read sequencing of Mycobacterium tuberculosis (https://doi.org/10.1099/mgen.0.000695)

First detection of porcine respirovirus 1 in Germany and the Netherlands (https://doi.org/10.1111/tbed.14100)

Critical steps in clinical shotgun metagenomics for the concomitant detection and typing of microbial pathogens (https://doi.org/10.1038/s41598-018-31873-w)

Expansion of Vancomycin-Resistant Enterococcus faecium in an Academic Tertiary Hospital in Southwest Germany: a Large-Scale Whole-Genome-Based Outbreak Investigation (https://doi.org/10.1128/aac.01978-18)

Trainer and organization for: Practical Introduction to Next-Generation Sequencing using Oxford Nanopore's MinION Platform for Microbiologists and Public Health Professionals, Huye, Rwanda, 2024.

• Food Pro-tec-ts
• European Union’s Horizon 2020 research and innovation programme (713660)
• The German Center for Infection Research
• The Beatrixoord Noord-Nederland Foundation
• EurHealth-1Health